Coming soon: solid state NMR of low gamma nuclei
We provide experimental and consultation service
to all Industry looking for NMR solution.
Our Services
Routine NMR and Structure
Routine 1D and 2D NMR (1H, 13C, 19F, 29Si, 31P, HSQC, HMBC, COSY, NOESY, ROESY, TOCSY, DOSY, etc)
Small molecule structure verification and Elucidation
Self-Diffusion NMR Chromatography
Routine 1D and 2D DOSY NMR
(Identification of molecules in a mixed matrix)
Polymer NMR
Routine 1D 1H and 13C qNMR for polymer chain length in PEG/PPG/co-polymers, linear or circular calixarenes.
Homo or Co-polymers, monomer quantification.
Protein NMR
1D and 2D HSQC for protein folding and stability check.
1D-3D NMR for structural characterization.
Protein Biophysics (SBDD)
Routine CSP NMR screening, Kd, hit validation, and lead optimization
Ligand Biophysics (FBDD)
Routine 1H and 19F NMR screening, and hit validation
Specialized techniques: STD, WaterLOGSY, FAXS, cFAXS, cSTD, DEEP-STD.
Integral Membrane Proteins (IMPs) in phospholipid bilayers
Solution and MAS solid state NMR for IMPs in phospholipid bilayers or nanodiscs.
Protein-Protein or Protein-drug interaction by NMR
MAS solid state NMR of APIs
1D CPMAS and 2D-HetCor NMR for quantification of amorphous and crystalline APIs in solid state.
A quick NMR screening for protein/antibody interaction.
Physicochemical properties
Solubility/Stability in organic and aqueous buffer, equilibrium Ksol, Tsol, PKa, LogD/LogP, forced degredation in acidic, basic, oxidative buffer.
